What will happen to killed T. pallidum when Anti-Human Globulin is added to the patient's serum?

When Anti-Human Globulin is added to the patient's serum containing killed Treponema pallidum, the appropriate response is that it will fluoresce or glow. This is due to the fact that Anti-Human Globulin, also known as Coombs reagent, is used to detect antibodies that are bound to the surface of cells or pathogens. In the case of T. pallidum, if specific antibodies are present in the patient's serum, the Anti-Human Globulin binds to these antibodies, forming larger complexes that can then be visualized using fluorescence techniques.

This reaction indicates the presence of specific antibodies against Treponema pallidum, either as a result of an ongoing or past infection, and the fluorescent response provides a means to confirm the interaction between the pathogen and the patient’s immune response. This is a typical method used in serological testing to identify and confirm infections, particularly syphilis caused by T. pallidum.

Other options do not represent the biochemical interactions occurring during this test correctly. For instance, disintegration is not meaningful in this context as the bacteria need to be intact to be recognized by the antibodies. Turning blue does not apply since there is no specific coloration that results from the addition of Anti-Human Glob